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22 files found:

  • Chapter 51: Effect of physical exercise on laboratory test results (1 ×)
    … Clinical Laboratory Diagnostics 51 Effect of physical exercise on laboratory test results Contents 51 Effect of physical exercise on laboratory test results 51.1 Blood and plasma volume 51.2 Complete blood count 51.2.1 Hemolysis 51.2.2 Reticulocytes 51.2.3 Pseudoanemia 51.2.4 Anemia diagnostics in endurance athletes 51.2. …
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  • Chapter 42: Bacterial infections (1 ×)
    … Clinical Laboratory Diagnostics 42 Bacterial infections Contents 42 Bacterial infections 42.1 Diagnosis of bacterial infections 42.1.1 Direct pathogen detection 42.1.1.1 Molecular biological methods 42.1.1.1.1 Important basic terms 42.1.1.1.2 Analysis using DNA probes 42.1.1.1.3 Target sequence amplification techniques 42. …
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  • Chapter 38: Pregnancy (1 ×)
    … Clinical Laboratory Diagnostics 38 Pregnancy Contents 38 Pregnancy 38.1 Laboratory findings in normal pregnancy 38.1.1 Hormones 38.1.2 Blood volume and hematopoiesis 38.1.3 Kidney function 38.1.4 Liver function 38.1.5 Hemostasis 38.1.6 Glucose metabolism 38.1.6.1 Gestational diabetes mellitus diagnosed early in pr …
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  • Chapter 36: Prolactin (PRL) (1 ×)
    … Clinical Laboratory Diagnostics 36 Prolactin (PRL) Contents 36 Prolactin (PRL) 36.1 Indication 36.2 Method of determination 36.3 Specimen 36.4 Reference interval 36.5 Clinical assessment 36.5.1 Macroprolactin 36.5.2 Clinical symptoms 36.5.3 Evaluation of prolactin levels 36.5.3.1 Hyperprolactinemia in fema …
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  • Chapter 35: Disorders of the pituitary-somatotroph axis (1 ×)
    … Clinical Laboratory Diagnostics 35 Disorders of the pituitary-somatotroph axis Contents 35 Disorders of the pituitary-somatotroph axis 35.1 Pituitary-somatotroph axis 35.1.1 Short stature 35.1.1.1 Laboratory results in suspicion of craniopharyngioma 35.1.2 Growth hormone (GH) 35.1.3 Insulin-like growth factor I (IGF-I) 35.1.4 …
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  • Chapter 34: Disorders of the pituitary-adrenocortical axis (1 ×)
    … Clinical Laboratory Diagnostics 34 Disorders of the pituitary-adrenocortical axis Contents 34 Disorders of the pituitary-adrenocortical axis 34.1 Pituitary-adrenocortical axis 34.1.1 Corticotropic cells of the anterior pituitary 34.1.2 Adrenal cortex 34.1.3 Adrenal corticosteroid biosynthesis 34.1.4 Glucocorticoid receptors …
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  • Chapter 29: Cancer associated syndromes (para neoplastic syndromes) (1 ×)
    … Clinical Laboratory Diagnostics 29 Cancer associated syndromes (para neoplastic syndromes) Contents 29.1 Para neoplastic disturbances of mineral and electrolyte metabolism 29.2 Para neoplastic disturbances of glucose metabolism 29.3 Para neoplastic disturbances of complete blood count 29.3.1 Anemia of malignancy 29.3.1.1 Warm autoimmune h …
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  • Chapter 28: Cancer biomarkers (1 ×)
    … Clinical Laboratory Diagnostics 28 Cancer biomarkers Contents 28.1 Malignant disease 28.1.1 Epidemiology 28.1.2 Causes of cancer 28.1.3 Classification of malignant tumors 28.1.4 Metastatic spread 28.1.5 Tumor microenvironment 28.1.6 Molecular biomarkers 28.1.6.1 Analytes of liqiuid biopsy for characterization of the g …
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  • Chapter 25: Autoimmunity and antibody testing (1 ×)
    … Clinical Laboratory Diagnostics 25 Autoimmunity and antibody testing Contents 25.1 Autoimmunity 25.1.1 Mechanisms of autoimmunity 25.1.2 Clinical characteristics of autoimmunity 25.1.3 Antibody testing of autoimmune diseases 25.1.3.1 Indication 25.1.3.2 Method of determination 25.1.3.3 Specimen 25.1.3.4 Reference int …
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  • Chapter 20: Cytokines and cytokine receptors (1 ×)
    … Clinical Laboratory Diagnostics 20 Cytokines and cytokine receptors Contents 20 Cytokines and cytokine receptors 20.1 Definition, classification, structure and function of cytokines 20.1.1 Cytokines 20.1.2 Cytokine receptors 20.1.2.1 Soluble cytokine receptors 20.1.3 Signal transduction 20.1.4 Function of cytokines 20.1 …
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  • Chapter 19: Inflammation (1 ×)
    … Clinical Laboratory Diagnostics 19 Inflammation Contents 19.1 Inflammation 19.1.1 Inflammation and innate immunity 19.1.2 Local inflammatory response 19.1.3 Course of an inflammatory response 19.1.4 Recognition mechanisms in the inflammatory response 19.1.4.1 Recognition by the complement system 19.1.4.2 Recognition by the a …
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  • Chapter 18: Plasma proteins (1 ×)
    … Clinical Laboratory Diagnostics 18 Plasma proteins Contents 18 Plasma proteins 18.1 Plasma protein diagnostics 18.1.1 Plasma protein synthesis and distribution 18.1.2 Plasma protein synthesis 18.1.3 Glycoproteins 18.1.4 Lipoproteins 18.1.5 Release of proteins into the plasma 18.1.6 Plasma protein distribution …
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  • Chapter 16: Hemostasis (1 ×)
    … Clinical Laboratory Diagnostics 16 Hemostasis Contents 16.1 Hemostasis: regulation and dysregulation 16.1.1 Introduction and overview 16.1.2 Vessel wall and endothelial cell 16.1.2.1 Interaction between the endothelium and platelets 16.1.2.2 Antiaggregatory effect of the endothelium 16.1.2.3 Interaction between the endothelium …
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  • Chapter 15: Hematology (1 ×)
    … Clinical Laboratory Diagnostics 15 Hematology Contents 15.1 Hematopoiesis 15.1.1 Clonal hematopoiesis of indeterminate potential (CHIP) 15.1.1.1 Blood count abnormalities in CHIP 15.1.2 Red blood cells 15.1.3 Thrombocytes (platelets) 15.1.4 Leukocytes 15.1.5 Hematopoietic system 15.1.5.1 Hematopoietic micro environmen
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  • Chapter 12: Kidney and urinary tract (1 ×)
    … Clinical Laboratory Diagnostics 12 Kidney and urinary tract Contents 12 Kidney and urinary tract 12.1 Clinical laboratory diagnosis of kidney and urinary tract diseases 12.1.1 Kidney functions 12.1.2 Kidney diseases 12.1.3 Acute kidney injury (AKI) 12.1.3.1 Definition of AKI 12.1.4 Acute renal failure (ARF) 12.1.4.1 Ac …
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  • Chapter 11: Toxic metals (1 ×)
    … Clinical Laboratory Diagnostics 11 Toxic metals Contents 11 Toxic metals 11.1 Laboratory investigation of toxic metals 11.1.1 Heavy metals 11.1.2 Indication for the determination of toxic metals 11.1.3 Specimen 11.1.4 Method of determination 11.1.5 Clinical significance 11.2 Aluminum (Al) 11.2.1 Indication 11.2 …
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  • Chapter 09: Acid base balance and blood gases (1 ×)
    … Clinical Laboratory Diagnostics 09 Acid base balance and blood gases Contents 9 Acid-base balance and blood gases 9.1 Acid-base homeostasis 9.2 Blood gases 9.2.1 CO2 transport in blood 9.2.2 O2 transport in blood 9.3 Indication 9.4 Method of determination 9.4.1 pH measurement 9.4.2 PCO2 measurement 9.4.3 PO …
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  • Chapter 08: Electrolyte and water balance (1 ×)
    … Clinical Laboratory Diagnostics 08 Electrolyte and water balance Contents 8 Electrolyte and water balance 8.1 Water balance and fluid compartments 8.1.1 Water and electrolyte balance 8.1.2 Diagnosis of water and electrolyte disorders 8.1.3 Osmotic equilibrium 8.1.3.1 Total body water 8.1.4 Fluid compartments 8.1.4.1 …
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  • Chapter 07: Iron metabolism (1 ×)
    … Clinical Laboratory Diagnostics 07 Iron metabolism Contents 7 Iron metabolism 7.1 Iron metabolism and disorders 7.1.1 Iron, an essential element 7.1.2 Critical determinants of iron homeostasis 7.1.2.1 Iron absorption and transport 7.1.2.2 Intestinal iron absorption 7.1.2.3 Iron uptake of the tissues 7.1.2.4 Plasma ir …
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  • Chapter 06: Bone and mineral metabolism (1 ×)
    … Clinical Laboratory Diagnostics 06 Bone and mineral metabolism Contents 6 Bone and mineral metabolism 6.1 Bone metabolism 6.1.1 Bone structure 6.1.2 Bone turnover (remodeling) 6.1.3 Regulation of bone metabolism 6.1.3.1 Osteoblast 6.1.3.2 Osteocyte 6.1.3.3 Osteoclast 6.1.3.4 Bone matrix 6.1.3.5 Mineralizati …
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  • Chapter 03: Carbohydrate metabolism (1 ×)
    … Clinical Laboratory Diagnostics 03 Carbohydrate metabolism Contents 3Carbohydrate metabolism 3.1Diabetes mellitus 3.1.1Classification of diabetes 3.1.2Epidemiology 3.1.3Type 1 diabetes (T1D) 3.1.3.1Diagnostic criteria for type 1A diabetes mellitus 3.1.3.1.1Recommended target levels for children with T1D 3.1.4Categories with increased r …
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  • Clinical Laboratory Diagnostics (1 ×)
    … Clinical Laboratory Diagnostics R11 Clinical Laboratory Diagnostics For my wife Eva, who passed away on June 21, 2023, and who gave her active support to the publication of Clinical Laboratory Diagnostics. List of contributors Volker Brade, Prof. Dr. med., Klinikum der Johann-Wolfgang-Goethe-Universität, em. Direktor des Instituts für Medizinische Mikrobiolog …
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